Modvigil 200 can increase alertness, energy, and attention in depressed individuals, particularly those who display signs of exhaustion, poor motivation, or cognitive slowness. Depression that is resistant to therapy may benefit most from it. It is not a replacement for therapy or medications, though. Individual effects may differ, and usage should only be advised by a physician. If not appropriately managed, modvigil side effects including anxiety or sleeplessness might exacerbate depressive symptoms.